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Identify cell doublets and triplets (1), cellular aggregates (2), protein aggregates (3), and plastic contaminants (4) in a cell therapeutic sample.

Decoding Cell Culture Contamination – An In-Depth Analysis

Reading Time: 11 minutes

Cell culture contamination is the bane of every laboratory’s existence. They can be physical, chemical, or biological, ranging from minor problems to catastrophes.  Solutions to contamination range from observing good laboratory practices, maintaining high standards of cleanliness and care of culture media, effective cleanups, and using technologies like Aura+ System to detect and characterize the contaminants, and potentially the source of contamination and...

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Embracing Sustainability in Analytical Science

Reading Time: 4 minutes

The integration of sustainability practices in analytical laboratories is not just a trend but a crucial shift towards a more responsible future. The ACQUITY QDa II Mass Detector shows how Waters enhances lab capabilities while also promoting sustainability.

Three scientists in a lab discussing particle size distribution

Complete Guide to Particle Size Distribution and Analysis

Reading Time: 8 minutes

Understanding your product’s particle size distribution can help you predict its manufacturability, efficacy, quality, bioavailability, and shelf life. Larger particles can decrease porosity, limiting the passage of the drug and potentially blocking it from reaching its target site.  Conversely, very small particles can add to the surface area of a drug, which can lead to unintended side effects. In short,...

Three scientists in a lab discussing particle size distribution

Particle Size Analyzer Prices 101

Reading Time: 6 minutes

In general, particle size analyzer prices can range from $35,000 to $250,000. The more an analyzer can do, the higher its price. It is also important to determine other factors that will add value to the right particle analyzer, including technology that allows tests using small samples, and that allows for particle testing earlier on in the discovery...

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USP<787>: Tailored Guidance for Better Biologics

Reading Time: 5 minutes

Understanding US<787> and its Impact on Pharmaceutical Quality with Tailored Guidance for Biologics In the world of pharmaceuticals, quality is paramount. Ensuring the safety and efficacy of medications is not only a regulatory requirement but also a moral obligation to patients. To achieve this, regulatory bodies like the United States Pharmacopeia (USP) lay down guidelines...

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Unseen Dangers: The Impact of Undetected Particles in Your Cell Therapies

Reading Time: 4 minutes

In recent years, cell therapy has emerged as a transformative treatment, providing promising cures and even more potential for treating various cancers and other diseases. However, amidst the optimism, a significant concern looms—the presence of foreign particles in cell therapy. These tiny intruders, often difficult to detect, can pose serious threats to the safety of...