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The Historical Role of Mass Spectrometry in Newborn Screening

Reading Time: 4 minutes

Newborn screening for inherited metabolic disorders dates to the early 1960s when Dr. Robert Guthrie in Buffalo, New York developed the first screening test for phenylketonuria (or PKU), a metabolic disease in which patients can’t metabolize the amino acid phenylalanine.

Nourishing Food and Water Research

Reading Time: 2 minutes

Opening this week in Singapore is a new resource for scientists in the challenging position of needing analytical insights as part of their food and water research, but who lack access to state-of-the-art instrumentation ... we’re so excited we wanted to share a preview!

Why Tandem Mass Spec is Essential for Newborn Screening

Reading Time: 3 minutes

Mass spectrometry has been game changer in newborn screening because rather than having a single test for a single condition, there was now a technique that provided a single test for a large number of different conditions.

I Resolve to Get Better mAb Separations

Reading Time: 3 minutes

We listened and learned how scientists separate mAbs and ADCs; then we designed a novel column for LC-MS bioseparations A critical step toward the prolific and successful use of monoclonal antibodies (mAb) as biotherapeutics occurred in 1988 when techniques were introduced to humanize these biomolecules, eliminating or reducing the deleterious patient side effects that previous...