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Charge Detection Mass Spectrometry (CDMS): Unprecedented Direct Measurement for the Characterization of Mega-Mass Biomolecules
Whether you are analyzing adeno-associated viruses (AAVs) or virus-like particles, nucleic acids such as RNAs or lipid nanoparticles (LNPs), proteins, or protein complexes, simple and fit-for-purpose tools with speed, accuracy, and precision are essential for driving biotherapeutic innovations forward. In recent years, scientists have increasingly turned to charge detection mass spectrometry (CDMS).
Recent Posts
Waters and the University of Tokyo Collaborate on Lipidomics Research
Digging deep into the human biome, Professor Yoshiya Oda of the Graduate School of Medicine at the University of Tokyo looks to ion mobility technology to uncover deposits of insight It’s an established fact that the more people age, the more they tend to engage with health care providers than they did when they were...
Sustainable Solutions for Plastics: The Future Role of Lignins
Plastics – Friend and Foe If you’re like me, you’ve probably seen images of all the floating plastic in the Great Pacific garbage patch or perhaps you’ve seen the images of wildlife rescuers trying to remove a plastic straw from a sea turtle’s nose. These images can be quite disturbing and destructive to the reputation...
5 Peptide Bioanalysis Sample Preparation Challenges (and how to overcome them!)
Scientists that have worked with peptides understand that peptide quantification can be challenging. One of the keys to successful peptide analysis is thorough and selective sample preparation. Sample preparation improves various aspects of chromatography and mass spectrometry analyses by utilizing solid phase extraction (SPE) to chemically separate different analytes and aid in removing the interfering...
The University of Neuchâtel Selects the SYNAPT™ XS to Enable Future Discoveries in Plant Metabolomics
After a comprehensive evaluation process, The University of Neuchâtel in Switzerland recently made the decision to add the newly released SYNAPT XS to their mass spectrometry instrument portfolio. Dr. Gaétan Glauser, a senior scientist at the Neuchâtel Platform of Analytical Chemistry (NPAC) facility, has core specialisms in plant analytical chemistry and metabolomics. Dr. Glauser and...
Sample Profiling of Pesticide Formulations Using UV and MS Detection for Component Identification
For the agricultural chemicals industry, the analytical quality control of pesticide products ensures that a consistent and effective product reaches the farm. More specifically, the detection, characterization, and quantitation of the active ingredient(s) as well as all other components in the formulation, including impurities and degradation products, are necessary to support product development, quality control,...
Nitrosamine Impurities: The Need to Verify
The recent nitrosamine impurity crisis has brought into question the quality of many APIs (Active Pharmaceutical Ingredients) produced and sourced for a number of popular drugs, resulting in product recalls, lost profits, and regulatory actions. Within a drug manufacturing process that is increasingly outsourced and globalized, companies manufacturing the API or in-sourcing the API or...
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