Interest in ion mobility mass spectrometry (IMS) technology is growing rapidly. The signs are everywhere. Since the year 2000, the number of abstracts submitted to ASMS mentioning ion mobility has grown more than 10-fold – from 30 to more than 350 in 2015. For most of that time, ion mobility has been available commercially in…
As regulators focus in on the critical quality attributes of biotherapeutics, what can biopharmaceutical labs in late development or QC do to increase confidence in their bioseparations – other than to run more assays?
According to published reports by Hiscox UK in 2008, just listening to the sound of a sports car increased salivary testosterone levels in male and female participants. Another study, by Gad Saad et al, measured a testosterone increase in men who were given the opportunity to drive a $150,000 Porsche 911 Carrera Cabriolet for an…
Tea is very important to them! If Waters Wilmslow ran out of tea it is likely the MS Research Team would struggle to function. The ancient Chinese Ruler, Emperor Jing Di, took tea to the grave with him for a cuppa in the afterlife. Many treasures were found in his tomb including; food, weapons, ceramic animals,…
On Wednesday evening after dinner and my usual digestif, I was watching the webcast “Making Ion Mobility Mass Spectrometry Routine” when my son walked by. “Wow dad, that’s kind of cool! What the heck is it?” he asked. “It’s ion mobility!! It’s an orthogonal and complementary resource for chromatography and mass spectrometry…” The digestif was…
Endangered analytical chemists face myriad obstacles today – lower than average job forecasts 1, costly and timely training, demand for more versatile knowledge, tighter regulations, and massive data management requirements. Perhaps most significantly, mass spectrometry market forecasts predict a lack of skilled users as a key market constraint2. Senior analytical chemists are presented with a…
Global trading of herbs and spices can be traced back for thousands of years. Historically they were considered a rare and precious commodity, but methods to determine their authenticity were only very basic, creating a compelling incentive to substitute with lower-value products with a low risk of the adulteration being discovered. This is clearly not…
NASA made history again recently as the spacecraft New Horizons successfully flew by Pluto, the last of the nine ‘classical’ planets, to gather valuable data about an area of our solar system that we know very little about. The spacecraft managed to successfully gather the most detailed images of Pluto ever seen whilst hurtling past…
For many years, the prevailing wisdom has been that in the event of chromatographic coelution, caused by complex samples, what is needed is a high-resolution mass spectrometer that can accurately identify different species contained within that single peak. However, even with the highest levels of resolution some ionisation patterns can be obscured by other species…
Sitting in the Waters’ John Dalton Suite in Wilmslow, England two weeks ago felt somewhat duplicitous. Here we were, in the part of the world considered the birthplace of Mass Spectrometry (MS), about to embark on a two-day workshop with 20 key collaborators and thought leaders to discuss Ion Mobility Spectroscopy (IMS), its use in contemporary structural…
The spatial distribution of molecules throughout a sample can provide a wealth of information regarding biological, physiological, and chemical phenomena and processes. One of the most recent and exciting developments in the study of molecular distributions has been the use of mass spectrometry (MS) to specifically measure molecular targets in order to determine their distribution…
Increasing Size, Complexity and Potency: The Bioanalytical Challenge of the Next Decade, was the theme for the 3-day APA India held in Mumbai, India from February 23-25, 2015. Close to 300 attendees gathered to discuss current trends and to offer strategies for overcoming these challenges moving forward. The second session of the morning was Bioanalysis:…