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Charge Detection Mass Spectrometry (CDMS): Unprecedented Direct Measurement for the Characterization of Mega-Mass Biomolecules
Whether you are analyzing adeno-associated viruses (AAVs) or virus-like particles, nucleic acids such as RNAs or lipid nanoparticles (LNPs), proteins, or protein complexes, simple and fit-for-purpose tools with speed, accuracy, and precision are essential for driving biotherapeutic innovations forward. In recent years, scientists have increasingly turned to charge detection mass spectrometry (CDMS).
Recent Posts
Reflecting on Lessons in Leadership This Veteran’s Day
Three Leadership Lessons Being a Veteran Taught Me Veteran’s Day is a time for us to honor those who served our country in the armed forces. It is a day that holds special meaning to me. As a cavalry officer in the United States Army, my experiences in both peacetime and combat shaped me as a...
Webinar Highlights – Improving Analytical Method Performance Through Quality Risk Management and a Design of Experiments Approach
In our most recent Method Lifecycle Management webinar held Improving Analytical Method Performance Through Quality Risk Management and a Design of Experiments Approach, Joseph A. Turpin, Director of Chromatography Products and Services at S-Matrix Corporation and Tran Pham, Business Development Manager at Waters Corporation, presented an overview of Quality by Design approaches to analytical method development (AQbD), the regulatory views on this approach, examples of design of experiments in AQbD, and case studies demonstrating software assisted AQbD method development.
Waters Opens New Swedish Head Office and Open Access Laboratory
On October 2, 2019, Waters proudly opened our new Swedish head office and laboratory in the House of Innovations, located in the center of Campus Solna next to Karolinska Institutet. The new facility features an open access laboratory designed to provide students, scientists and startup companies with an experienced technical staff and easy-to-use automation infrastructure...
Data Integrity Matters: Limiting Access to Tools That Could Be Used to Manipulate Data (Part 4)
Suppressing Peak Integration Being able to optimize peak integration and identification, whether by resetting the method RT settings, manually identifying peaks or suppressing integration of specific known peaks are certainly tools which, in the wrong hands, with the wrong intent and without a robust training and review process, may be used by unscrupulous staff to...
Mobile Phase Additives for Peptide Characterization
The characterization of peptides and proteins can be challenging due to issues such as adsorption, varying hydrophobicities, and specificity to name just a few. When analyzing peptides by Liquid Chromatography (LC) and Mass Spectrometry (MS), it’s beneficial to introduce mobile phase additives in order to facilitate ionization and enhance the analyte signal. Additionally, these additives...
Supporting the Next Generation of STEM Professionals
As a science-based organization, STEM education is of the utmost importance to Waters. This blog highlights the excitement of its partnership with Junior Achievement, one of the world’s largest youth-serving NGOs that prepares young people for employment and entrepreneurship.
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