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OligoWorks SPE Kits: Boosting Oligonucleotide Bioanalysis Efficiency
New OligoWorks Solid Phase Extraction (SPE) Kits for extraction and bioanalysis of oligonucleotides deliver advantages over liquid-liquid extraction (LLE) and other existing SPE kits and sample preparation methods. Read on to discover how.
Recent Posts
Enhancing Analytical Productivity by Breaking Down Silos (Part 1)
Analytical methods transfer. Data integrity. A changing and more stringent regulatory landscape. All this, and more, impacts productivity in upstream and downstream biopharmaceutical processes. How is Waters looking to help address development challenges for biologics and biosimilars?
Data Integrity Matters | What do you do with Orphan Data Created during Data Acquisition?
Halting a chromatographic analysis where the system is not performing correctly or when another error is evident in the separation is a valuable and scientific way to avoid creating unusable data that needs to be subsequently invalidated following a defined analytical lab error/result SOP. But what do you do with that orphan data?
The Expanding Role of Mass Spec for Peptide Mapping in Multi-Attribute Monitoring Assays
There are two primary multi-attribute monitoring (MAM) assay choices for biologic development and QC: subunit protein mass analysis and peptide mapping by LC-MS. Here we explore how peptide mapping LC-MS MAM workflows are being used.
Webinar Highlights: Quantifying Cannabinoids in Oral Fluid to Determine Driving Impairment Following Marijuana Consumption
Q&A from a recent forensic toxicology webinar on using an ACQUITY UPLC I-Class/Xevo TQ-S micro MS system for quantifying cannabinoids in oral fluid.
Multi-Attribute Monitoring: The Expanding Role of Mass Spectrometry for mAb Subunit Analysis
Two MAM approaches for biotherapeutic analysis are being implemented today; one focused on the analysis of monoclonal antibody (mAb) subunits, and the other focused on the analysis of peptides from a protein digest (peptide mapping workflow). Both have their advantages and disadvantages. Here, we explore MAM for mAb subunit analysis.
How to Detect Fipronil in Eggs: Tips for Pesticide Screening Laboratories
We discuss analytical options using LC and GC with MS/MS to detect the pesticide fipronil in eggs for food safety testing.
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