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Charge Detection Mass Spectrometry (CDMS): Unprecedented Direct Measurement for the Characterization of Mega-Mass Biomolecules
Whether you are analyzing adeno-associated viruses (AAVs) or virus-like particles, nucleic acids such as RNAs or lipid nanoparticles (LNPs), proteins, or protein complexes, simple and fit-for-purpose tools with speed, accuracy, and precision are essential for driving biotherapeutic innovations forward. In recent years, scientists have increasingly turned to charge detection mass spectrometry (CDMS).
Recent Posts
Tools for Chromatographic Success: Three Ways to Support Data Quality in Routine Analysis
Avoiding the pitfalls of data quality and integrity in the Pharma QC laboratory while running routine analyses is an ongoing challenge. Regulatory violations are frequently a result of a lack of complete data, suspect data, and improper audit trails. A recent report from Deloitte stated that data integrity violations account for over 70% of the...
Boosting Biopharma Productivity with Routine LC-MS
As scientific advances continue to carry researchers into new arenas, it is vital that technology evolves in tandem. At Waters, we understand that it is only by leveraging fit-for-purpose technologies that researchers are able to unleash their creativity and make pioneering scientific breakthroughs. Scientists working within the rapidly growing biopharmaceutical industry are no exception. With...
Simple Joys: Giving Thanks in a New World
There’s a longstanding debate among historians about whether America’s first Thanksgiving feast at Plymouth Colony in fall 1621 included turkey. Yet, today there’s no disputing that this bird has become a symbol and centerpiece of America’s Thanksgiving celebrations. This Thanksgiving Day staple has also played a significant role in food safety by enabling the discovery...
USEPA Approves APGC Tandem Quadrupole Mass Spectrometry as Alternative Test Procedure for Dioxin Analysis
A Breakthrough in Dioxin Analysis for Environmental Laboratories In September, the United States Environmental Protection Agency (USEPA) recognized the use of atmospheric pressure gas chromatography (APGC) with tandem quadrupole mass spectrometry (MS) as an acceptable alternative to traditional high-resolution magnetic sector mass spectrometry for USEPA Method 1613. The recognition frees laboratories to adopt the Waters...
Need to Improve Database Scoring for LC/MS Metabolomics? Try ACQUITY Premier Columns!
After another wrong assignment, I knew there had to be a better way to improve my database matching! Spectral library matching is an integral component in the workflow of untargeted, or high resolution mass spectrometry, analyses such as urine or plasma metabolomics. The comparison of non-disease and disease state samples can give insights to potential...
Honoring our Veterans Around the World
Around the world, November 11th is time to honor those who have served their countries through military service. To some it’s Veterans Day, to others it’s Remembrance Day. This year we want to spotlight a few of the Veterans that make the Waters difference. Our Veterans Employee Circle, as part of the Diversity and Inclusion...
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