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Slalom Chromatography: A High-Speed Path to Nucleic Acid Separation
Slalom chromatography is no longer just a scientific curiosity, it’s a comeback story. Once sidelined due to limited reproducibility and unclear mechanisms, this technique is now gaining momentum thanks to the rise of nucleic acid therapeutics and advances in UHPLC systems. But its revival wasn’t accidental. It took a year-long deep dive into DNA physics,…

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Agro Food industry Hi Tech article: Ensuring the Consistency and Quality of Food and Beverages with New Advancements in Mass Spectrometry
by Joe Romano Joe Romano is Senior Manager of Waters’ Food and Environmental Business and a member of the AgroFood Industry Hi Tech Scientific Advisory Board In his recently published article in AGRO Food Industry Hi Tech, author Joe Romano says that in order to ensure long-term success in a highly competitive global market, food, beverage,...
Full Spectrum Molecular Imaging: More Than Just Pretty Pictures
The spatial distribution of molecules throughout a sample can provide a wealth of information regarding biological, physiological, and chemical phenomena and processes. One of the most recent and exciting developments in the study of molecular distributions has been the use of mass spectrometry (MS) to specifically measure molecular targets in order to determine their distribution...
Move Over LIMS… There’s a New Alternative for the Lab
Powerful alternative to LIMS offers seamless lab-to-business connection for science-driven organizations Are you in the market for a Lab Information Management System (LIMS)? An alternative to the traditional LIMS systems is the new NuGenesis Lab Management System. NuGenesis Lab Management System combines high impact functionality with a high degree of flexibility, readily adapting to your...
The Answer to Fast, Sensitive, and Simple Released N-Glycan Profiling and Characterization
How quickly can you go from glycosylated protein to glycan fragment confirmation? Now, analyzing released N-glycans takes about as much time as it does for Tom Brady and the New England Patriots to erase a 10-point deficit and win a football game. An exaggeration? Perhaps, but with the help of the new Waters GlycoWorks...
Have we bridged the gap between qual and quan using HRMS?
Increasing Size, Complexity and Potency: The Bioanalytical Challenge of the Next Decade, was the theme for the 3-day APA India held in Mumbai, India from February 23-25, 2015. Close to 300 attendees gathered to discuss current trends and to offer strategies for overcoming these challenges moving forward. The second session of the morning was Bioanalysis:...
Chapter and Verse: USP 621 and You
In August 2014, the United States Pharmacopeia and the National Formulary (USP-NF) put into effect new guidelines to “allowable adjustments” in its Chapter <621> (USP37-NF32 S1). And as of August 1, 2016 when USP 39 NF 34 S1 goes into effect, for <621> nothing significant has changed since. The USP doesn’t publicize changes to their...
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