Technology

Our expertise drives innovation, development, and application of informatics and software that continue to enable leading pharmaceutical, environmental, food & beverage and chemical materials organizations to accelerate decision-making, improve laboratory effectiveness, and get products to market faster.

  • The Waters ACQUITY Arc System Receives 2016 Frost & Sullivan New Product Innovation Award

    Bridging the gap between HPLC and UPLC performance, the ACQUITY Arc System is a favorite of QC laboratories that test small and large molecule pharmaceuticals. We’re excited to announce today (Tuesday, Oct. 5) that our ACQUITY® Arc™ System has just received a 2016 New Product Innovation Award from market research and growth consulting firm Frost…

  • Is using Microflow LC in an Industrial Setting Really that Cumbersome?

    Microflow or nanoflow chromatography has been used mostly in the academic and fundamental research environment in the past for its various advantages over analytical liquid chromatography, but rarely in the industrial settings. This is most likely because many of us believe it is a pain-in-the-neck technique to perform! But is this a reality or just…

  • Method Scaling in Preparative HPLC: Analytical Method &
    Preparative Method

    Andrew Aubin (Andy): Manager, Purification / SFx Systems Marketing Laboratory & Blogger VOC: Voice of the Chemist VOC:  “I tried to scale up my analytical HPLC method to prep and it didn’t work.” Andy:  This is one of the most common things we hear from chemists wanting to do preparative chromatography. We also hear the following…

  • What is microflow LC?

    What are the differences between micro-scale and conventional LC? Microflow (a.k.a. microscale) LC has been widely applied to proteomic research for years. Recently, as microflow LC-MS systems continue to evolve, more and more laboratories in various fields are weighing the implications of applying this small-is-beautiful technology. In this and my next two blog posts, I will discuss…

  • What do you get if you combine mass spectrometry with 5000 cups of beer, 1000 glasses of wine, and 600 servings of mac ‘n’ cheese?

    … A successful ASMS 2016! ASMS is definitely one of the highlights of our year and here at Waters we are only just recovering from this year’s event and, can you believe it, starting to think about next year already.  It’s funny because whenever I travel to America my children are always slightly suspicious that…

  • Binary vs. Quaternary Pumps: High Pressure Mixing vs. Low Pressure Mixing

    Welcome to the next installment in my series on binary vs. quaternary pumps for liquid chromatography! In my previous post, I discussed how gradients are created as well as the importance of having accuracy and precision in your gradient. Today I am going to talk about what happens after all that — specifically, mixing. After chromatographic…

  • Binary vs Quaternary Pumps: How is a Gradient Created?

    How is a Gradient Created? Any liquid chromatograph (LC) is an amalgamation of a certain set of components that delivers to the scientist a monograph of the sample they are analyzing.  Traditionally, an LC system consists of a pump, an injector, a column heater, a detector, and even more commonly these days a mass spectrometer…

  • Has Your Dinner Menu Been Quantified?

    For decades, food security was viewed exclusively through the lens of shortages. In the 1960s, when daily food availability in emerging countries was just 1,850 kcal per person as many as half of the world’s population was malnourished. It’s easy to understand our narrow focus on increasing food production. The challenges we face have shifted….

  • Pumping Ions – An Exercise in Engineering Sensitivity Into the Xevo TQ-XS Mass Spectrometer

    The challenge: Create the most sensitive mass spectrometer for quantitative analysis. That’s a tall order for any design engineering team. When given that assignment for a next-generation, tandem quadrupole mass spectrometer, our design engineers first spoke to those for whom analytical sensitivity means the most: scientists doing quantitative studies for demanding clients relying on accurate…

  • High-throughput Microscale Bioanalysis is not a Paradox

      Question: When someone says microscale chromatography, what comes to mind? Increased sensitivity? Reduced sample volume? Enhanced MS sampling efficiency? Yes, yes, and yes! You might also say, “finicky,” “slow,” or “only one person in our group knows how to use it!” Maybe even, “there’s no way I can successfully transfer that method, so why…

  • Tandem Quad Mass Spectrometry: The Foundation of Product Safety, Efficacy, and Decision-making

    There is a rightfully high expectation from consumers that the amounts of compounds and ingredients that producers report in their goods are accurate down to trace levels.  Whether personally or professionally, we all rely on this analytical information coming from laboratories that enables critical decisions to be made. Analytical chemists have been performing quantitative studies…

  • What’s the big deal about ion mobility mass spectrometry?

    Ion mobility spectrometry (IMS) is a technique that differentiates ions based on their size, shape, charge, and mass. While often used in small, portable devices at airports and remote locations for rapidly detecting small molecules whose mobility is known (for example, certain narcotics and explosives) when coupled with liquid chromatography-mass spectrometry (LC/MS), IMS provides an…