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Improving, Retaining, and Separating Polar Compounds Using Chromatographic Techniques
Separating and retaining polar compounds are significant challenges in chromatography. Here, we explore the key technical considerations and solutions for effectively handling these compounds, focusing on advanced chromatographic techniques and column technologies. What Are Polar Compounds? Polar compounds are essential in biological processes, drug design, and industrial applications due to their ability to interact with…
Recent Posts
Which LC Detector Should I Buy?
You might not like the answer… So the other day, I was with a customer when they asked me, “Viet, there are so many detectors out there! How do I know which one I need?” To which I answered with the one comment that all of you will love to hate, “It depends!” Detectors for...
Analytical Chemists Are Going Extinct?
Endangered analytical chemists face myriad obstacles today – lower than average job forecasts 1, costly and timely training, demand for more versatile knowledge, tighter regulations, and massive data management requirements. Perhaps most significantly, mass spectrometry market forecasts predict a lack of skilled users as a key market constraint2. Senior analytical chemists are presented with a...
Multiple Attribute Monitoring of Biopharmaceuticals Using Mass Detection
Multiple attribute monitoring has become a hot topic of discussion within biopharmaceutical organizations as the methodology allows detection and measurement of more critical quality attributes than conventional methods. Waters recently sponsored an outstanding webinar on this topic, hosted by Genetic Engineering News and presented by our own Biopharmaceutical Senior Manager, Sean M. McCarthy, Ph.D. Watch...
Waters COI Partner brings food fraud into the spotlight again
Global trading of herbs and spices can be traced back for thousands of years. Historically they were considered a rare and precious commodity, but methods to determine their authenticity were only very basic, creating a compelling incentive to substitute with lower-value products with a low risk of the adulteration being discovered. This is clearly not...
NASA’s New Horizons set the standards, Waters Xevo users benefit
NASA made history again recently as the spacecraft New Horizons successfully flew by Pluto, the last of the nine ‘classical’ planets, to gather valuable data about an area of our solar system that we know very little about. The spacecraft managed to successfully gather the most detailed images of Pluto ever seen whilst hurtling past...
Ion mobility: Providing better answers for age-old problems
For many years, the prevailing wisdom has been that in the event of chromatographic coelution, caused by complex samples, what is needed is a high-resolution mass spectrometer that can accurately identify different species contained within that single peak. However, even with the highest levels of resolution some ionisation patterns can be obscured by other species...
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