ACQUITY UPLC System End-of-Life Notification

Dear Valued Customer,

Thank you for choosing Waters as your Ultra Performance Liquid Chromatography (UPLC) solution provider.

For over 60 years, Waters Corporation has focused on improving human health and well-being through the application of high-value analytical technologies and industry leading scientific expertise. We have continually pioneered chromatography, mass spectrometry, and thermal analysis innovations, pursuing every opportunity to Deliver Benefit™ to our customers, employees, shareholders, and society.

Since the inception of ACQUITY UPLC in 2004, our portfolio for UPLC and UHPLC separations has grown considerably, fueled by constant innovation to meet the diverse and changing needs of our customers. As we continue to focus on bringing new technologies to the market, we have decided to initiate an end-of-life process for Waters' first UPLC system - the ACQUITY UPLC System (aka ACQUITY Classic). There is a limited quantity of ACQUITY UPLC Systems still available, which you can order until stock is depleted. 

This process will not impact the IVD version of the system.

We apologize for any inconvenience this may pose.

Affected products:


Please note that all ACQUITY UPLC Systems sold between now and March 31, 2021 will be fully warranted. We will provide full service & support for seven years to our current customers from last date of manufacturing, which is expected to be no later than March 31, 2021. It is anticipated that ACQUITY UPLC systems will move to Limited Support as of July 1, 2028.

Contact your Waters Instrument Specialist to discuss the best replacement options and strategy for your laboratory. We recommend exploring the ACQUITY UPLC I-Class PLUS with Fixed Loop Injection System, which offers the most equivalent performance to the ACQUITY UPLC System. Additional systems to consider are the ACQUITY UPLC H-Class PLUS Binary System, which is available in both stainless steel and biocompatible formats.

Additionally, the FlexUP Technology Renewal Program will be available to your laboratory if your ACQUITY UPLC System is greater than seven years old. Through this program, your laboratory can realize significant savings on the trade-in of your existing ACQUITY UPLC System for another Waters LC system.

For more information, please download the end-of-life letter.