System Performance Standards

This standard mix is used to confirm the benchmark performance of a Preparative/Purification System through fraction collection. This particular Quality Control (QC) Reference Material is specially formulated to allow the user to verify correct fraction collection. This test is highly valuable to perform upon first use/installation, and any time the system has not been used or has had any changes. Contains 3 compounds including Thionin, Thioflavin, and Crystal Violet.

The LCMS QC Reference Material is a 9 component mix of Acetaminophen, Caffeine, Sulfaguanidine, Sulfadimethoxine, Val,-Tyr-Val, Verapamil, Terfenadine, Leucine-Enkephalin and Reserpine packaged in a Waters crimp top vial for direct injection. This standard provides a comprehensive reference for the use with LC-MS or MS instrumentation with a wide variety of conditions and methods.

Individual Components in the LCMS QC Reference Material Mix

This standard mix should be used to confirm the benchmark performance of your Preparative/purification system. This particular suitability standard is a specially formulated mix that includes a void marker, neutral, acidic and basic compounds. It can be used with a variety of column chemistries and dimensions, and system hardware. Contains 5 mg/mL each of Diclofenac sodium salt, Diphenhydramine hydrochloride, and Flavone in DMSO.

This standard mix should be used to confirm the benchmark performance of your analytical HPLC or UPLC System. It is a significantly complex Quality Control (QC) Reference Material in that it contains compounds which could be challenging to separate. This standard is designed to provide this complexity and is appropriate when complex assays are routinely performed. It can be used with a variety of column chemistries and dimensions, and system hardware. The Reversed-Phase QC Reference Material contains 7 compounds including uracil, butyl paraben, naphthalene, propranolol, dipropylphthalate, acenaphthene, and amitriptyline at pH 7. This particular QC Reference Material is a specially formulated mix that includes a void marker, neutral, acidic, and basic compounds.

This standard is extremely versatile and appropriate for a vast variety of column chemistries and dimensions, and system hardware. It is adaptable to a wide variety of separation methods. The Neutrals QC Reference Material is a mixture of Acetone, Naphthalene and Acenaphthalene in 50/50 acetonitrile and water. It is specially formulated to provide system assessment information quickly and easily. These compounds are well-separated and provide good peak shape in UV at 254 nm on analytical chromatographic systems in good working order.

The HILIC QC Reference Material was designed as a standard to help benchmark this type of separation. It is a 4 component mix containing an un-retained void marker, a polar neutral compound and two polar basic compounds that provides a stable chromatographic separation for HILIC columns and was specifically designed as a batch test standard for ACQUITY UPLC^® BEH HILIC Columns. It is packaged in a Waters Crimp Top vial for direct injection and contains 1 mL of each component in the below concentration in a matrix of 90% Acetonitrile/10% 100 mM Ammonium Formate pH 3.00.

Quadrapole: Tuning, Gradient, Sensitivity and Precision Standard: Routine Use MS Standard for Single and Triple Quads. Perform tuning gradient performance sensitivity and precision testing. Contains Acetominophen, Caffeine, Sulfadimethoxine, Verapamil, Chloramphenicol, and 17-α-hydroxy-progesterone.

Resolution Check on all GCMS Products: Routine Use MS Standard for all GC/MS products. Perform resolution check testing. Contains Heptacosafluorotributylamine Standard.

CI optimization on GCTs: Routine Use MS Standard for GCTs only. Perform CI optimization on GCT's only testing.  Contains 2, 4, 6 -Tris(trifluoromethyl)-1, 3, 5 - triazine.

FI optimization on GCTs: Routine Use MS Standard for FI optimization on GCTs only.  Contains: Perfluorotrimethylcyclohexane, Heptacosa, Hexafluorobenzene, Pentafluorobenzene, Chloropentafluorobenzene, Xylene
and Acetone.

CI/FI optimization and Tuning on GCTs: Routine Use MS Standard for GCTs only.  Perform CI/FI optimization and Tuning on GCTs only. Contains Chloropentafluorobenzene.

Calibration/tuning on Autospecs: Routine Use MS Standard for Autospec.  Perform Calibration/tuning on Autospecs only.  Contains Perfluorokerosene.