Tof-MRM for the Confirmation of Fentanyl Analogues for Forensic Toxicology

Library Number:
APNT135011515
Part Number:
720006515EN
Author(s):
Michelle Wood and Tom Rosano
Source:
Waters, Albany Medical Center
Content Type:
Application Notes
Content Subtype:
Application Notes
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The objective of this current analytical work was to evaluate the performance of Tof-MRM – a targeted mode of acquisition, which is also available on the same HRMS platform and to develop a confirmatory method for the fentanyl class. A secondary aim was to utilize a previously reported novel technique i.e., Threshold Accurate Calibration (TAC), for matrix normalization without the requirement for deuterated internal standards.


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