Liquid chromatography-mass spectrometry (LC-MS) is a well-established tool for the identification and quantification of small molecules in research and industrial settings, but the technique has only recently moved into the healthcare arena. This cutting-edge technique has transitioned to a higher-throughput, safer, and lower-cost alternative to immunoassays for routine testing – enabling smaller labs to adopt the technology with ease. As newer techniques continue to be developed for the clinical laboratory, the analysis of molecules within biological matrices has become more sensitive, specific, and sophisticated, with fewer pre-analytical steps required from lab personnel. Small molecule analysis can be performed on a variety of sample types in a clinical research setting—including whole blood, serum, plasma, urine and cerebrospinal fluid (CSF). However, one of the key success factors for a proper analysis is sample preparation. Choosing the right sample clean-up method can sometimes be bewildering.
A streamlined and clean sample preparation:
Having cleaner samples means longer column lifetime, less instrument downtime and minimize costs in manpower and equipment maintenance. In a word, Sample Prep makes your analytical lab more productive and offers more sensitive and reproducible LC-MS analysis.
Sample preparation is often introduced as a major bottleneck, i.e. the most difficult and time-consuming step. However, Waters provides valuable documentation regarding your sample preparation challenges. Download our resource kit to get application notes, scientific articles, webinars & testimonials.
Waters sample preparation solutions for quantitative analysis make it easy to deliver a sample that is reproducible, yields high recovery and is free of interferences. Based on a simple, logical workflow that provides clean samples through selective separations, Waters sample preparation products maximize sensitivity, increase throughput and spur the development of robust methods.
One of Waters major concerns is to help users developing a fit-for-purpose method. Waters manufacturers are there to help. Together, we can evaluate various options to determine the best fit for your lab.
Marie Lee - Clinical Consumable Specialist, UK and Northern Europe. Listen to Marie telling how she helps labs choose the right sample prep technique for their workflow.
Lab workflow, data tracability, Waters clinical hub for knowledge sharing... let our experts introduce you to Waters' wide range of clinical applications and solutions.
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