Oligonucleotides Separation Technology Columns

Oligonucleotide Separation Technology (OST) columns contain second-generation hybrid-silica BEH Technology™ particles functionalized with C₁₈. The separation of detritylated synthetic oligonucleotide samples is based on the well-established method of ion-pair, reversed-phase chromatography.

This chemistry delivers exceptional sample resolution and superior column life. In addition, Waters manufacturing and quality control testing procedures help ensure consistent batch-to-batch and column-to-column performance regardless of application demands.

The availability of 1.7 μm UPLC^® technology or 2.5 μm HPLC particles in various column dimensions gives you the flexibility to meet various lab-scale isolation or analysis needs.

Features:

• Scalable reversed-phase HPLC columns for lab-scale purifications
• Increased sample through-put with maintained component resolution with UPLC Technology
• LC/UV and LC/MS methods for enhanced quantitative and qualitative analyses
• Exceptional column life using Waters patented Ethylene-Bridged (BEH Technology) Hybrid particles

* OST Custom Column

** Values are only approximates and vary depending on oligonucleotide length, base composition, and “heart-cutting” fraction collection method used.