ACQUITY UPLC HSS Cyano (CN) Column, 100Å, 1.8 µm, 2.1 mm X 150 mm, 1/pk

To get exceptional peak shape and reproducibility in low- to mid-pH conditions, you need UPLC technology and a column that’s more than up for the task. That’s where the ACQUITY UPLC HSS Cyano (CN) Column comes into consideration. Thanks to the general-purpose propyl-cyano bonded phase, this cyano column offers superior peak shape for bases and increased retention of polar compounds. That balance between polar- and non-polar functionalities is achieved because of this column’s unique chemistry. What’s more, this ACQUITY UPLC Column is fully scalable and transferable to HPLC separations. That kind of flexibility has been desired by scientists everywhere, and we’re happy to deliver with the ACQUITY UPLC HSS CN Column.

The ACQUITY UPLC HSS Cyano Column was built with method development scientists in mind, as it can help you easily develop robust methods that are compatible with all modern chromatographic detection modes. To add to that flexibility, this CN column also offers low hydrophobicity and unique selectivity when compared to straight-chain alkyl columns. And thanks to the High-Strength Silica base particle, this column is able to achieve ultra-stable retention under demanding conditions. You need only look at the ACQUITY UPLC HSS Cyano Column’s pH range to see that’s true.

All ACQUITY UPLC Columns are classified by their terrific separation power and efficiency, but what else do they offer?
For one, ACQUITY UPLC separation technology can help chromatographers harness the increased flow rates of UPLC and improve analyte sensitivity all at once. With more than 50 column dimensions and configurations in the ACQUITY UPLC family, you’re sure to find the right match for your LC-MS analyses.

With superior separation performance comes other considerations, though. To keep the ACQUITY UPLC HSS Cyano Column performing at its best, you need to follow proper column cleaning and regeneration directions. But if you’re using various chemicals and solvents in the same column, particulate fouling can become a concern. That’s why we recommend equipping your analytical column with an ACQUITY UPLC HSS Cyano (CN) VanGuard Pre-column. The pre-column threads easily into your analytical column for a seamless column protection workflow.

The scientific community at large is always changing, and scientific companies like Waters must keep up with these rapidly changing times. That’s why when you shoplab equipment at Waters, you’ll truly find everything you need to be successful in the lab. That includes lab informatics, quality control reference materials and so much more.