Chemistry |
Cyano (CN) |
Separation Mode |
Reversed Phase |
Particle Substrate |
Silica |
pH Range Min |
2 pH |
pH Range Max |
8 pH |
Temperature Limits |
45 C |
Maximum Pressure |
18000 psi (1240 Bar) |
Endcapped |
No |
Silanol Activity |
High |
Particle Shape |
Spherical |
Particle Size |
1.8 µm |
Endfitting Type |
Parker-style |
Pore Size |
100 Å |
Format |
Column |
Surface Area |
230 |
System |
UHPLC, UPLC |
Particle Technology |
HSS |
USP Classification |
L10 |
Inner Diameter |
2.1 mm |
Length |
100 mm |
Carbon Load |
5 % |
eCord |
Yes |
UNSPSC |
41115709 |
Brand |
ACQUITY UPLC |
Product Type |
Columns |
Units per Package |
1 pk |
ACQUITY UPLC HSS Cyano (CN) Column, 100Å, 1.8 µm, 2.1 mm X 100 mm, 1/pk
After extensive research, Waters has produced the ACQUITY UPLC HSS Cyano (CN) Column, which is an ultra-performance general-purpose propyl cyano bonded phase that provides superior peak shape for bases, increased retention, and extremely long column lifetimes at low pH. The ACQUITY HSS CN brand contains columns that are fully scalable and transferable to HPLC separations.
The ACQUITY HSS packing materials that are used in the ACQUITY UPLC HSS Cyano (CN) Column have been designed specifically for use with the Waters ACQUITY UPLC System and are manufactured in a cGMP, ISO 9001:2000 certified plant using ultra-pure reagents. To be certain of excellent, reproducible performance by the lab equipment, each batch of ACQUITY HSS material is tested chromatographically with acidic, basic, and neutral analytes, and the results are held to narrow specification ranges. Every column is also individually tested and a Performance Chromatogram and Certificate of Batch Analysis are provided on the eCord™ intelligent chip.
The ACQUITY UPLC HSS Cyano (CN) Column provides low hydrophobicity and unique selectivity when compared to straight-chain alkyl columns. The lab equipment offers ultra-stable retention, exceptional peak shape, and reproducibility under low-to mid-pH conditions. This is made possible by the innovative monofunctional cyano bonding with protective alkyl-side chains. In addition to this, the ACQUITY UPLC HSS Cyano (CN) Column offers a unique attribute that is compatible with both reversed-phase and normal-phase techniques.
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What Is The Recommended pH Range For ACQUITY UPLC HSS Cyano (CN) Column?
The recommended operating pH range for ACQUITY UPLC HSS Cyano (CN) Column is 2-8. It is important to note that the column lifetime will vary depending upon the operating temperature, the type, and concentration of buffer used. For instance, the use of phosphate buffers at pH 8 in combination with elevated temperatures will lead to shorter column lifetimes.