XSelect Premier Columns

XSelect Premier Columns

Maximize selectivity with problem-solving technologies for a wide range of analytes

Maximize selectivity with problem-solving technologies for a wide range of analytes

Get the best injection to injection reproducibility in your chromatographic separations with Waters XSelect Premier 2.5 µm Columns, which utilize MaxPeak High Performance Surfaces (HPS) Technology. Ideal for the wide range of analytes encountered in method development, XSelect Premier Columns combine modern particle technologies and ligands with the protection of MaxPeak HPS Technology. 

Designed to maximize selectivity, XSelect Premier Columns are built on one of two innovative base particle technologies, Charged Surface Hybrid (CSH) and High Strength Silica (HSS). The integration of MaxPeak HPS allows you to achieve balanced, controlled interactions between your analytes, mobile phase, and the analytical column for the highest performance chromatographic separations.


Waters offers a wide selection of XSelect Column chemistries.

Waters offers a wide selection of XSelect Column chemistries.

Specifications

Overview

  • Reduces column conditioning and passivation for higher productivity
  • Maximizes selectivity with excellent stability at low pH
  • Improves sensitivity and peak shape for basic compounds
  • Increases reproducibility from analysis to analysis, for more confidence in analytical results
  • Prolongs column lifetimes with optional VanGuard FIT format 

Recommended Use: For improving selectivity, peak shape, and retentivity in method development.


XSelect Premier Column Featured Technologies

XSelect Premier Column Featured Technologies

MaxPeak HPS Technology
  • Reduce analyte/surface interactions
  • Increase analyte recovery
  • Better peak shape
  • Increase sensitivity
VanGuard FIT*
  • All-in-one guard, plus column design
  • Achieve longer column lifetimes
  • Easy installation

* Specific to columns noted with VanGuard FIT

XSelect Premier CSH Column Characteristics

XSelect Premier CSH Column Characteristics

XSelect Premier CSH C18 Columns
  • Alternative selectivity to existing C18 columns
  • Low anion exchange
  • General purpose hybrid columns
  • Improved peak shape for bases with low pH mobile phase
  • Reduction in analyte/surface interactions
  • Excellent pH stability
  • VanGuard FIT column option
XSelect Premier CSH Phenyl-Hexyl Columns
  • Alternative selectivity for aromatic compounds
  • Medium anion exchange
  • General purpose hybrid columns
  • Improved peak shape for bases with low pH mobile phase
  • Reduction in analyte/surface interactions
  • Excellent pH stability
  • VanGuard FIT column option

XSelect Premier HSS Column Characteristics

XSelect Premier HSS Column Characteristics

XSelect Premier HSS T3 Columns
  • Excellent reversed-phase retention for polar analytes
  • 100% water wettable
  • General purpose silica columns
  • High retention
  • Reduction in analyte/surface interactions
  • Excellent low pH stability
  • VanGuard FIT column option

The selectivity you need for method development

Maximize selectivity while minimizing variability with Waters XSelect Premier Columns, which provide the chemistries to enhance selectivity for method development while preventing unwanted analyte-surface interactions that can cause variability.

Two base particles, HSS and CSH, provide enhanced selectivity for acidic, basic, and neutral compounds across a wide pH range. For formic acid mobile phases, XSelect Premier CSH C18 Columns are the first choice for method development. You can enhance selectivity for aromatic compounds with XSelect Premier Phenyl-Hexyl Columns. Finally, increase retention for polar compounds under reversed-phase LC conditions with XSelect Premier HSS T3 Columns, which are compatible with 100% aqueous mobile phases.


The results you want. None of the interactions you don’t.

When developing analytical methods, having the confidence that analytes will not interact with metal ions in the flow path is critical. Analyte/surface interactions can lead to poor peak shape, analyte loss/misidentification, and ultimately costly sample re-work. The MaxPeak HPS Technology found in Waters XSelect Premier Columns significantly reduces unwanted analyte/surface interactions, so you can be sure you’re seeing everything in your sample --from the first injection on.




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Related

Get superior selectivity and peak shape for basic compounds with XSelect HPLC and UHPLC columns. Discover our CSH and high-strength silica columns.

Experience the highest level of chromatographic performance, flexibility, and assurance while mitigating unwanted analyte/surface interactions with MaxPeak Premier Columns.

Confidently produce the most accurate, reliable, and reproducible data. The Arc Premier System provides right first time robust results from the very first injection, reliably and easily.

Prolong analytical column lifetime while maintaining chromatographic performance with VanGuard Pre-columns and cartridges.

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