SQ Detector 2

Acquire data with confidence

IntelliStart Technology automates system setup so that non-expert users can acquire data with confidence with the knowledge that the system is operating optimally. An integrated system of fluidics, electronics, and software continually monitors system performance, helps users tune for optimum sensitivity, creates optimized single ion recording (SIR) analysis methods, and enables easy reporting of whole system performance. Through a series of diagnostic checks, the mass spectrometry (MS) detector reports when it is ready for use. Any failures trigger a red-light system status, which warns that action may be required before analysis can proceed.

A mass range as wide as you’d need

With a mass range of 3000 m/z, the SQ Detector 2 makes mass confirmation of large molecules easier than ever before, allowing users to see higher mass peaks, and giving them more confidence in their mass assignments.

Versatile for today, futureproofed for tomorrow

Designed for optimum compatibility with multiple chromatographic separation techniques, the SQ Detector 2 is perfectly placed to help users extract more knowledge from their analyses. The SQ Detector 2 is compatible with UPLC, UPC², HPLC, preparative HPLC, and preparative SFC, as well as direct analysis with the ASAP probe.

With the universal ion source architecture of the SQ Detector 2 family, your lab can use the widest range of ionization techniques and the latest innovations in ionization technologies, providing limitless choice in experimental options. When users need options and time is critical, the ion sources are quickly interchangeable and ready to use within minutes.

Walk-up accessibility

The OpenLynx Open Access Application Manager provides walk-up access for LC-MS operation in laboratories whose chemists have varying levels of instrumental analysis experience. OpenLynx also provides customizable batch processing to support the large amounts of data generated by high-throughput analyses. To accelerate the learning curve for instrument operation, OpenLynx leads users through sample submission, method selection, and reporting options. These routine analyses can be performed more efficiently when chemists submit their own samples, leaving instrumentation experts more time to focus on advanced analyses.

Simplify Biologics Mass Confirmation Directly in Empower

Empower Software in-line deconvolution extends the value of SQ Detector 2 for biologics laboratories by converting complex, multiply charged MS spectra into clear molecular mass information directly within the chromatography workflow. With its broader mass range, SQD2 is well suited to biologics mass confirmation workflows where higher-mass species, oligonucleotides, antibody-drug conjugates (ADCs), peptides, glycans, and other large-molecule modalities need to be assessed with confidence. This capability helps scientists identify product variants, monitor impurities, and confirm critical quality attributes, without unnecessary complexity, specialist data handling, or disconnected software steps.

Optimize performance and reproducibility with ZSpray source architecture

Integral to the Universal Ionization Source, Waters patented ZSpray technology means that users get optimum performance and excellent reproducibility from their analysis. Providing exceptional resistance to contamination by involatile buffers, the unique dual orthogonal pathway gives superior separation of ions from neutrals, keeping the instrument cleaner for longer. This results in less downtime, higher laboratory efficiency, and better instrument utilization.