Arc HPLC System
Highly reliable, low complexity, accurate routine analysis for all
Ever-evolving regulations are impacting liquid chromatography (LC) method approaches for product quality control and beyond. With the Waters Arc HPLC System, you can count on high-efficiency separations and quality data to meet your regulatory requirements with confidence.
With Arc HPLC System, you can easily replicate and improve the performance of your existing LC methods without compromising data quality eliminating the burdens of older, less efficient LC systems. Rugged and dependable, Arc HPLC System delivers the ideal balance of performance and value for right-the-first-time analysis.
Arc HPLC System
Specifications
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Maximum operating pressure |
9500 psi |
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pH range* |
1–12.5 |
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Operating flow rate range |
Up to 5.000 mL/min |
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Sample flow path |
Stainless-steel |
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Sample carryover |
≤0.002% (Caffeine) under UV conditions |
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Sample compartment |
4–40 °C |
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Sample capacity |
768 [2x 384-well plate]; or 96 [2mL vial holders] |
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Pump options |
Quaternary |
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Solvent conditioning |
Passive and active pre-heating |
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Column tracking |
eCord Technology tracks column usage and history |
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Column capacity |
1 to 3 columns capacity, up to 7.8 mm ID and 300 mm length. |
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Detector options |
Tunable UV/Detector (TUV) Photodiode Array Detector (PDA) Fluorescence Detector (FLR) Charged Aerosol Detector (CAD) Refractive Index Detector (RI) Evaporative Light Scattering Detector (ELSD) Conductivity Detector (CD) Electrochemical Detector (ECD) ACQUITY QDa Mass Detector (QDa) |
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External control |
Empower Chromatography Data System |
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Physical specifications (QSM-R, SM-FTN-R, 30cm CH) |
Width: 57.4 cm (22.6 in.) Height: 57.1 cm (22.5 in.) Depth: 62.8 cm (24.7 in.) |
Overview
- Enhance performance without redeveloping your method
- Run methods with greater robustness over traditional HPLCs
- Easily replicate and enhance existing HPLC methods with low analyte carryover, high injection precision, and high back pressure tolerance
- Seamlessly receive transferred methods from other HPLC platforms, preserving analyte retention time and reproducibility of your analysis
- Support compliance with Empower Chromatography Data System (CDS), the gold standard, compliant-ready software
Recommended Use: Delivering the ideal balance of performance and value for right-the-first-time analysis and trusted test results.
Features Header
Precision for your most stringent assay requirements
Meeting strict assay requirements can be a challenge. With the Arc HPLC System, the USP assay for losartan potassium met all the system suitability requirements, including injection precision <0.5%. Comparison of the Arc HPLC System to competitive high-performance liquid chromatography (HPLC) systems demonstrates leading performance in USP efficiency, USP tailing, and injection precision.
Seamless transfer without changing your existing methods
With the Arc HPLC System, easily transfer existing methods from the instrument, laboratory and resources used to develop the original method. Achieve equivalent test results without compromising method integrity or changing validated gradient tables. If necessary, Gradient SmartStart can be used to make adjustments due to dwell volume differences between the sending and receiving systems.
The HPLC performance you expect
The Arc HPLC System uses quaternary gradient formation that performs as well as many binary HPLC systems. In a side-by-side comparison for challenging separation at high flow rates, the system delivered similar retention time stability and superior peak area repeatability compared to a competitive binary system.
Improve your productivity and efficiency
When methods are scaled to smaller particles (e.g., from 5 μm to 3.5 μm), the resulting backpressure typically increases, and the resolution improves. The high-pressure limit of the Arc HPLC System allows the use of high flow rates with smaller particle columns to gain efficiency, reducing the analytical run time and mobile phase consumption. As shown in the image, the resolution of a critical pair of analytes (peaks 5 and 6) improved as a result of method scaling on the Arc HPLC System.
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