Antibody and Protein Therapeutics
Accelerate antibody and protein therapeutics development, from characterization to commercialization.
Protein Attribute Analysis
Power and accuracy, with confidence
Strengthen product quality insights with robust,scalable methods and integrated techniques to provide the mostadvanced understanding across biotherapeutic discovery,development, and manufacturing
Intact Mass and Subunit Analysis: Screen samples for quick,accurate confirmation of molecular weights and glycoforms
Peptide Mapping: Characterize and monitor protein critical qualityattributes at the peptide level, with confidence
Multi Attribute Analyses (MAM): Reduce analytical burden bycombining analysis of attributes into fewer methods
Glycan Analysis: Enhance profiling with fast, complete workflows andcomprehensive, user-friendly tools
Higher Order Structure
Complete understanding of structural detail. No guesswork.
Support comparability studies, formulation development and analytical development activities to establish the Critical Quality Attributes (CQAs) that influence the safety and efficacy of the therapeutic
Biophysical Characterization: Understand physical and chemical properties to ensure drugs meet rigorous regulatory guidelines for safety, quality, and efficacy
HDX-MS: Characterize structural details with confidence, with dedicated hardware, software and automated workflows
Lifecycle Operations
Optimize quality and compliance with solutions from discovery to manufacture.
End to end protein therapy development requires exceptionalanalytical performance, from discovery through commercialization.
Host Cell Protein (HCP) Analysis: Detect and remove trace levels to ensureoptimum product quality and reduce immunogenic risk.
QC and Release Testing: Ensure consistent product quality and safety,streamline regulatory compliance and support faster product approval.
Quantitative Bioanalysis: Assess drug safety and monitorbiotransformation to guide critical decisions during development.
Bioprocessing: Build robust processes, faster with in-line, on-line andat-line PAT tools.
Amino Acid Quantitation: Optimize yield and manufacturingconsistency with precision.
Modality-Specific Analytics
Streamline product development. Understand your molecule.
Achieve accurate analysis across diverse therapeutic modalitieswith Waters dedicated solutions.
Bioconjugates: Streamline the development, analysis and manufacture ofconjugated biologics with automated methods and data processing
Biosimilars: Accelerate the development of biosimilar candidates withrobust comparability assessment
Synthetic Peptides: Achieve unparalleled resolution and sensitivityacross every aspect of peptide analysis
GLP-1 Receptor Agonists: Enhance GLP-1 development, from drugdiscovery to manufacturing, with solutions to eliminate analytical uncertainty
