MaxPeak Premier OBD Preparative Columns
Achieve predictable scale-up for challenging molecular targets prone to interactions
Achieve predictable scale-up for even the most challenging molecular targets with Waters MaxPeak High-Performance Surfaces (HPS) Technology, now with new 10 & 19 mm internal diameter inert prep columns! The expanding Waters MaxPeak Premier Columns family now offers full scalability to preparative dimensions, giving scientists greater confidence in recovery while driving productivity. Eliminate the hassle of tedious column conditioning and easily streamline your workflow.
These advanced columns minimize non-specific adsorption (NSA), enabling precise detection of even the most elusive low-level compounds. With exceptional recovery and scalability, they deliver high yields and purity, whether you are working with UPLC or preparative workflows.
Engineered to tackle the toughest challenges, MaxPeak Premier OBD Preparative Columns bring unmatched efficiency, scalability, and purity to your lab. Transform your process with a simple column change—and watch your results soar.
MaxPeak Premier OBD Preparative Columns
Specifications
Overview
Achieve predictable scale-up for even the most challenging molecular targets
Get full scalability to preparative dimensions
Reduce tedious column conditioning and streamline workflows
Minimize NSA for precise detection of elusive low-level compounds
Recommended Use: To minimize non-specific adsorption and enable precise detection of the most elusive low-level compounds with high recovery and scalability.
MaxPeak Premier OBD Preparative Columns Characteristics
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BEH (Ethylene Bridged Hybrid) columns — best in class stability at low and high pH -
Compatible with a variety of mobile phase additives or buffers for faster method development
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Multiple pore diameters available, optimized for a comprehensive selection of molecule sizes
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CSH (Charged Surface Hybrid) columns — best peak shape for basic compounds at low pH
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HSS (High Strength Silica) columns — increased retention for polar and non-polar compounds
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Offers the widest selectivity range of base particles and ligands
Reversed-phase preparative columns for peptides
Obtaining reversed-phase separations of biotherapeutic peptides like next-generation insulins and GLP-1 receptor agonists can be challenging. Waters has purposely selected four peptide QC batch-tested, reversed-phase column chemistries to help address existing separation challenges.
Our MaxPeak High Performance Surface Technology based analytical and lab scale OBD Preparative Columns and step-by-step guidance help bridge the gap from successful analytical to isolation of highly purified target products.
Preparative solutions for oligonucleotides
Using stainless steel column hardware for oligonucleotide purification can cause challenges. Unwanted secondary interactions can cause coelution with impurities, leading to low recovery and irreproducibility.
By switching to MaxPeak Premier Oligonucleotide Preparative Columns, you can ensure high recovery, consistent and reliable impurity profiling from the first injection.
Learn more about MaxPeak Premier OBD Oligonucleotide Columns
Preparative solutions for organic acids
Preparative separations are purposeful and practical, meant for isolating targets from mixtures. Purification outcomes can be off target, compromising compound purity, recovery, and turnaround times.
With inert hardware, Waters MaxPeak Premier OBD Preparative Columns provide predictable scale-up from analytical MaxPeak Premier Columns, giving you confidence in recovery and boosting your productivity.
Bridge the gap from analytical to prep
With the Waters Preparative OBD Columns Calculator, you’ll have the scale-up tools you need for mass load scaling and gradient scaling with appropriate flow rate scale-up and volume consumption prediction, as well as calculations for split flow ratios for mass spectrometer-driven chromatography and focused gradient UPLC to preparative method transfer.
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