 
            
        This is an Application Brief and does not contain a detailed Experimental section.
This application brief highlights the analysis of propranolol in Rat plasma using XTerra C18 columns.
Propranolol in rat plasma has been analyzed in this application brief.
 
            
        | Column: | XTerra MS C18 2.1 x 30 mm, 3.5 μm (p/n: 186000398) | 
| Mobile phase A: | 1.0% NH4OH | 
| Mobile phase B: | ACN | 
| Isocratic mobile phase composition: | 50% A; 50% B | 
| Flow rate: | 0.2 mL/min | 
| Injection volume: | 50 mL | 
| Detection: | MS ESI+ | 
| Instrument: | Alliance 2790, Micromass Quattro Ultima | 
| Ion source: | ESI+ | 
| Source temp.: | 150°C | 
| Gas cell: | 1.5e-3 mbar, 25 eV | 
| Desolvation temp.: | 350 °C | 
| Cone gas flow: | 150 L/hr | 
| Drying gas flow: | 600 L/hr | 
| Cone voltage: | 20 V | 
 
            
         
            
        WA20738.092, June 2002