OneLab is the software backbone of Waters Lab Automation. Whether you are guiding a single pipette or orchestrating a fully robotized workstation, OneLab gives every scientist the tools to build reproducible, traceable, and compliant workflows — without writing a single line of code.
Browser-based, zero-install simplicity OneLab runs entirely in your browser. Open a tab, design a protocol, and execute it on Andrew+ or Pipette+ from your PC, tablet, or any device on the network.
Drag-and-drop protocol design Build liquid handling methods visually using OneLab's graphical editor. Drag steps, define volumes, assign labware, set parameters — then save, version, and share protocols instantly across users, labs, and sites. No scripting.
60+ ready-to-use protocols Get started immediately with a growing library of validated, open-source methods covering serial dilutions, plate reformatting, SPE, PCR prep, Peptide Mapping, sample normalization, and more. Use them as-is or customize them to fit your specific workflow.
Built for regulated environments OneLab supports 21 CFR Part 11 and EU Annex 11 compliance with electronic signatures, role-based access control, full audit trails, and complete traceability — from aspiration to dispense, from user to instrument, from calibration to result. Every action is recorded automatically, eliminating manual logbooks and reducing compliance overhead.
Connected to the entire Waters ecosystem OneLab orchestrates Andrew+ Robot, Pipette+ Stand, and every connected device — Extraction+, Heater-Shaker+, Peltier+, Magnet+, Shaker+, and more — from a single interface. It also integrates with Empower, MassLynx, and waters_connect, creating a seamless digital thread from sample preparation through to analytical results.
Full traceability and data integrity Every protocol execution generates a complete, tamper-evident record: who ran it, when, on which instrument, with which pipette, which tips, and which calibration status. OneLab turns every experiment into an auditable, reproducible digital asset — strengthening data integrity across your entire operation.