With dispersion of less than 10 μL, the ACQUITY UPLC H-Class System delivers the highest resolution of any quaternary LC system in the market.
Achieving true UPLC performance requires that system dispersion (or extra-column band spread) be matched to the peak widths associated with narrowbore columns packed with sub-2-μm particles. While other systems might be designed for high pressure, it doesn’t mean they're designed to deliver the sharp peaks associated with UPLC performance and the ACQUITY UPLC H-Class System.
Comparison of the same method with the same column on a low-dispersion ACQUITY UPLC H-Class System versus a higher-dispersion UHPLC system.
Improve your methods by scaling them to UPLC.
Get your analytical results faster and decrease the cost of analysis per sample. Waters’ intuitive tools make it simple, from the reversed-phase column selectivity chart, to the ACQUITY UPLC Columns Calculator.
With functionality that allows you to easily compensate for system differences, the ACQUITY UPLC H-Class System was designed to help you transition your existing methods, improve your efficiency, and meet the increasing demands on your laboratory.
Get the versatility to discover the the best set of chromatographic conditions for your sample, providing a more robust method. The flexibility of the ACQUITY UPLC H-Class System allows you to automatically screen important method parameters, including:
Changes in peak elution order, due to different pH conditions programmed with Auto-Blend Plus, were easily tracked with the ACQUITY QDa detector for this example of metoclopramide and its related compounds.
Completely automate the screening process by combining the ACQUITY UPLC H-Class System with method development software tools such as the Empower Sample Set Generator and Fusion software. And, adding mass detection with the ACQUITY QDa Detector allows you to easily track peaks, significantly reducing post-analysis time.
Support both HPLC and UPLC methods
Need an LC platform that can run your HPLC methods today before you begin the transition to UPLC? The ACQUITY UPLC H-Class System was designed to support both HPLC and UPLC methods so that you can invest in your laboratory’s future but still support your existing methods until you're ready to deploy UPLC.
Limited time offer! Request info on how the ACQUITY QDa could be in your lab now!
Mass spectral data. Complete separations. Within the same analysis. Within the same workflow.
Laboratories around the world are converting to ACQUITY UPLC H-Class.
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See how Waters solves common challenges on the path to world-class drug development.