If you are performing routine analyses or developing methods, or just prefer the flexibility of multi-solvent capabilities in a quaternary-based system, the only choice has been HPLC. Until now.
The ACQUITY UPLC H-Class System is a streamlined system that brings together the flexibility and simplicity of quaternary solvent blending and a flow-through-needle injector to deliver the advanced performance expected of UPLC type separations – high resolution, sensitivity and improved throughput – while maintaining the robustness and reliability that ACQUITY UPLC systems are known for.
Choosing the ACQUITY UPLC H-Class System enables you to continue running existing HPLC methods on a forward-looking LC platform that allows you to confidently and seamlessly transition to UPLC separations, when you’re ready, using integrated system tools and reliable column kits for method transfer and method development that simplify migration.
Auto•Blend Plus technology significantly reduces the time you spend in the prep lab by automating the formulation of mobile phases from reservoirs of pure solvents or concentrated stock solutions. It enables you to take full advantage of the ACQUITY UPLC H-Class System's quaternary blending capabilities. Auto•Blend Plus manages the desired pH and ionic strength requirements for the selected mobile phase.
This technology makes routine analyses easier to manage and easier to execute by reducing the amount of work to be done in preparing complex mobile phases. Easily transfer methods to other laboratories, and make the laboratory process more efficient by reducing the possibility for errors.
Method development - robust, reliable, and predictable
Turn a tedious and time-consuming process with HPLC into a versatile and productive workflow with UPLC.
The ACQUITY UPLC H-Class System features a variety of components to improve data quality, increase sample throughput, and reduce cost per analysis for timely and predictable results.
ACQUITY UPLC Method Development Kits offer combinations of different column chemistries to accommodate your method development approach, enabling methods to be developed efficiently and effectively.
Method transfer made easy
With the ACQUITY UPLC H-Class System, you won't have to think twice about transferring methods to and from any LC instrument.
With unprecedented selectivity and reproducibility across batches and particle sizes, our Method Transfer Kits preserve the integrity of a separation as it is transferred to and from HPLC and UPLC platforms. And choosing the right UPLC columns and conditions couldn't be easier with the method transfer guidelines provided by the ACQUITY UPLC Columns Calculator, available on the system console.
With the ACQUITY UPLC H-Class System, your laboratory can achieve UPLC-quality separations without changing the way you work. The familiar design of the ACQUITY UPLC H-Class System's Quaternary Solvent Manager (QSM) and Sample Manager (SM-FTN), with flow-through needle design, gives you all the flexibility and usability of your current HPLC while still achieving the highly efficient separations that only UPLC can provide.
See how the ACQUITY UPLC H-Class System's Quaternary Solvent Manager and Sample Manager operate.
Learn how to automate buffer combinations, and make your entire laboratory process more efficient.
Spend your lab time conducting analyses - not making buffers.
Update your LC System. Or upgrade the way you work.
Get mass spectral data, and ensure the most complete separation for your methods.
Within the same analysis. Within the same workflow.
Laboratories around the world are converting to ACQUITY UPLC H-Class.
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See how Waters solves common challenges on the path to world-class drug development.