Atmospheric Pressure Chemical Ionization (APCI) is an effective method for analyzing lower-polarity compounds. The high-efficiency IonSABRE™APCI probe offers significant improvements in sensitivity compared with earlier versions of probe, particularly at higher liquid flow rates.
With APCI, the sample stream is nebulised and analytes are desolvated using a combination of gas flow and high temperatures. The desolvated compounds are ionized by charge transfer as they pass through a plasma created by a corona discharge. Flow rates up to 2 ml/min are acceptable.
The IonSABRE APCI probe with thermally enhanced heater design provides improved heat distribution and sample vaporization. The support gas flow also maximizes transmission of sample droplets into the ion source.
Together, these features provide optimum APCI performance leading to superior limits of quantitation in compound quantification and identification studies.
The IonSABRE APCI probe is available for the following MS instruments:
*An additional conversion kit is included with the LCT Premier IonSABRE probe option to allow Ion Sabre APCI Exact Mass experiments.
Equipment and Installation
The accessory kit comprises:
Although the accessory is easy to install, Waters strongly recommend installation and operation confirmation/training by a Field Service Engineer.