If your lab needs to qualitatively identify metabolites, lipids and proteins in complex samples and extract high resolution quantitative information from a single injection, SONAR delivers increased confidence by getting the right answer first time and reduces the time to results.

SONAR provides increased selectivity compared to a conventional DIA experiment while collecting data at UPLC compatible speeds. By sliding a resolving quadrupole window over a specified mass range during an MS scan, the quadrupole separates co-eluting precursor masses by scanning the mass range, and transiting them in sequence. Fragment ions from different precursors can then be recorded separately and assigned with confidence. SONAR provides data for quantitation and identification in a single injection.

Improved Laboratory Efficiency

• Short LC run times: SONAR operates at UPLC speeds, fast enough to fully describe these narrow LC peaks.
• Reduces intervention for data processing: Cleaner spectra allow automated data processing*.
• Confidence of MS/MS data: Accurate mass of every precursor ion is known and assigned, eliminating the need for time consuming method development to optimize MS/MS parameters.
• Fewer sample injections: Quan/Qual achieved from a single injection

Increased Confidence in Results

• Enhances data quality: Cleaner data removes ambiguity in compound assignments, increasing confidence and removes the need for repeat analysis
• Improved library search: Cleaner data boosts confidence with the reliability and accuracy of results.
• Strong data processing options: SONAR data is compatible with Symphony, Progenesis QI, and Skyline.

Learn more about how SONAR works.