Literature

Analysis and Purification of Synthetic Oligonucleotides, DNA Restriction Fragments, PCR Products and Plasmids by HPLC

This application note demonstrates the use of optimized IP-RPLC and a compliance-ready benchtop Tof instrument for the quality assessment of PCR test reagents used in the SARS-CoV-2 CDC assay.

This infographic demonstrates that, the BioAccord system can answer your scientific questions quickly, easily, and without LC-MS experience.

The objective of this white paper is to discuss the data processing app called MS Quan that will deliver the ability to quantify and report data on the waters_connect platform for Waters tandem quadrupole mass spectrometer-based LC-MS systems.

This application note demonstrates, the development of a stability indicating method used to monitor Tenofovir alafenamide fumarate drug substance after exposure to forced degradation conditions. An automated, statistical approach was employed by utilizin...

This application note demonstrates the steps of a method development based on design of experiments approach using the ACQUITY UltraPerformance Convergence Chromatography (UPC²) System. The studied compounds belong to statin class, used for lowering high ...

This application note demonstrates the Amino acid analysis (AAA) by high-performance liquid chromatography has its own unique challenges due to the chemical and physical properties of the analytes.

This application brief demonstrates the use of RADIAN ASAP with LiveID to swiftly identify adulterated cocoa butter. LiveID enabled us to transform complex raw MS data into simple-to-interpret chemometric models.

This application note demonstrates the analysis of complex matrices can cause column performance issues when performed routinely.

This application note demonstrates the original ACQUITY UPLC methods developed for amino acid analysis have been successfully adapted for the ACQUITY UPLC H-Class PLUS Binary System with no loss of performance.

This application note demonstrates about HILIC-MS/MS method which provides a good solution for the screening and quantification of AMGs in foods.

This application note demonstrates about the BioAccord LC-MS System, which enables waters_connect users to perform rapid and accurate intact mass confirmations for small and medium size oligonucleotides (up to 50-mers).

This application note demonstrates the ability to assess the inertness of the recently introduced ACQUITY Premier System, which has been designed to eliminate metal-analyte secondary interaction.

ACQUITY Premier Columns and LC systems were designed with MaxPeak High Performance Surfaces Technology to address the variability in the analysis of metal-sensitive analytes such as oligonucleotides. The ACQUITY Premier Solution offers out-of-the-box perf...

LC columns designed and QC tested for analytical separations of amino acids, glycans, oligonucleotides, peptides, and proteins.

This poster presented at virtual PFAS conference from December 6-10 for the 2021,held at Michigan.

This application note demonstrates the Drug and pill testing is a harm reduction measure that aims to reduce the adverse health consequences of drug consumption at music festivals and other settings. Pill testing has been conducted in a range of global ju...

Waters MaxPeak Premier Columns enable scientists to have more control over their chromatographic separations with the inclusion of MaxPeak High Performance Surfaces (HPS). MaxPeak HPS are innovative technologies designed to increase analyte recovery, sens...

This application brief demonstrates the use of difluoroacetic acid (DFA) ion pairing and a 2.7 µm 450 Å phenyl bonded stationary phase to quickly separate the AdV proteins while obtaining high sensitivity mass spectra.

This application note demonstrates the benefits of applying an acquisition-centric data reduction algorithm, intelligent data capture (IDC), on the Xevo G2-XS System for Multi-Attribute Method (MAM) Studies.

This application note demonstrate that the ACQUITY Premier LC Technology is robust and capable of delivering consistent results across LC platforms and is well suited to support the analytical needs of labs across an organization.

This application demonstrates the quantitative and qualitative capabilities of the Xevo G2-XS QTof and its suitability for oligonucleotide bioanalysis. We also demonstrate comparable performance with the Xevo TQ-XS Triple Quadrupole Mass Spectrometer for ...

This application brief describes a simple, rapid, and effective cleanup strategy to remove co-extractives from porcine and bovine liver extracts. This is executed via Oasis MCX 96-well SPE plate processed using Otto SPEcialist.

This application note describes the utilization of the LipidQuan Workflow7 to develop a polarity switching method for the quantification of the key lipid species involved in the biomolecular processes associated with prostate cancer and the Response to Va...

In this application note, we show that the size of several sgRNAs could be estimated by comparison to a Low Range ssRNA Ladder (50–500 bases) using an optimized anion-exchange method developed on a Waters Protein-Pak Hi Res Q Column