Comprehending COVID-19: Application of UniSpray and Electrospray Ionization for the Detection of Proteolytic Digested SARS-CoV-2 Proteins

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Stuart Oehrle, Laurence Van Oudenhove, Jan Claereboudt, Hans Vissers, Bart Van Puyvelde, Simon Daled, Katleen Van Uytfanghe, Dieter Deforce, Maarten Dhaenens
Waters, University of Ghent
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In this application brief, we have compared a novel ionization technique UniSpray with Electrospray ionization to further optimize the LC-MS detection method (720006967 and 720006968) for selected SPIKE and NCAP tryptic peptides and investigate the potential increase in dynamic range and selectivity of this LC-MS method.

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