Investigations into a Novel Ion Mobility Separator Comprising a Travelling Wave Enabled RF-Only Stacked Ring Ion Guide
The separation of ion species according to their mobilities in
a buffer gas is a technique that has been around for over thirty years.
It has been successfully used in portable devices for rapid detection
of chemical warfare agents and for the detection of explosives and
illegal drugs. More recently the technique has been applied to more
fundamental investigations into the structure and conformation of
biomolecules. The classical Ion Mobility Separator uses a static DC
voltage gradient to drive ions through the buffer gas. Reported here is
a new approach to mobility-based separation of ions using a travelling
voltage wave in an ion guide.