New Tools for Improving Data Quality and Analysis Time for Chemical Library Integrity Assessment (2007 poster)

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Marian Twohig, Paul Lefebvre, Darcy Shave, Warren B. Potts III, and Rob Plumb
HPLC 2007, June 17-21, Ghent, Belgium
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The identity and purity of a candidate pharmaceutical is critical to the effectiveness of the drug screening process. LC/MS is employed extensively in drug discovery in order to exclude false positives and maintain the high quality of the product. This process can be very time consuming and can potentially delay the progression of a drug through the discovery process. Thus sample throughput is a critical issue in moving compounds from the hit to lead status. Ultra Performance LC® leverages sub 2 mm LC particle technology to generate high efficiency faster separations.

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