UPLC™ MS-MS Determination of Enrofloxacin and Ciprofloxacin in Chicken Tissue

Library Number:
WA43233
Part Number:
WA43233
Author(s):
KimVan Tran and Michael S. Young [Waters]
Source:
AOAC 2006
Content Type:
Posters
Content Subtype:
AOAC
Related Products:
 
 
Straightforward SPE protocols were used to prepare chicken tissue samples for analysis using UPLC-MS-MS. Tandem SPE using both cation and anion-exchange retention of the amphoteric fluoroquinolone antibiotics provides excellent sample enrichment and cleanup. UPLC-MS analysis was performed in electrospray negative mode without ion-pairing mobile phase. Lower detection limits and much faster analysis times were obtained compared with traditional HPLC

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