Analysis of Intact Protein Species Using a Novel Travelling Wave Ion Mobility Device Coupled with a Time of Flight MS
In this presentation we will show data acquired using a novel
hybrid Quadrupole/TWIMS/oa-Tof mass spectrometer, operated with an ESI
source. The TWIMS is a stacked-ring ion guide, operated at elevated
pressure, with opposite phases of an rf voltage applied to adjacent
plates to provide radial ion confinement. A continual sequence of dc
pulses is superimposed on the confining rf to provide waves which
propel ions through the gas.