Improved Glycopeptide Fingerprinting and Mass Spectra for Characterization of Recombinant and Isolated Glycoproteins

Library Number:
720001727EN
Part Number:
720001727EN
Author(s):
Beth L. Gillece-Casto, Thomas E. Wheat, Ziling Lu, and Jeffrey R. Mazzeo
Source:
ASMS 2006 May 28 - June 1 Seattle, Wa
Content Type:
Posters
Content Subtype:
ASMS
Related Products:
ASMS Glycoproteins II Chromatographic resolution provides excellence in mass spectra of glycopeptides. High resolution separation of glycopeptides has been achieved on 300A and 130A pore size 1.7 ƒÊm particles.Good peak shape is obtained for sialylated and nonsialylated glycopeptides including positional isomers. Changing the gradient slope, temperature or mobile phase modifier can optimize separations. Data obtained in MS only mode produced spectra characterizing complex sialylated glycan structures.

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