TECHNIQUE FOR UPLC-UV/MS METHOD DEVELOPMENT OF PHARMACEUTICAL PURITY ANALYSIS

Library Number:
720001533en
Part Number:
720001533en
Author(s):
Michael D. Jones and Andrew J. Aubin
Source:
Pittcon 2006
Content Type:
Posters
Content Subtype:
Pittcon
Related Products:
 
In this poster, we will demonstrate the increased resolution and throughput achievable by “Ultra Performance Liquid Chromatography” (UPLC™ ) and show how the increased sensitivity combined with single quadrapole MS allows the identification of more impurities when compared to a conventional HPLC method that might be used today. Method development tools such as peak tracking by single quadrapole MS and usage of chromatography simulation software is applied to increase efficiency and confidence in the quality of the data collected.

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