Stuctural Elucidation of an Unknown Impurity Present in a Simvastatin Impurity Profile Utilizing Sub 2 µm Porous Particle LC Combined with oa-TOF, MS/MS, and MS(E)

Library Number:
720002264EN
Part Number:
720002264EN
Author(s):
Michael D. Jones, Emma Marsden-Edwards, Robert S. Plumb, Peter Alden, Paul D. Rainville, and Jose Castro-Perez
Source:
HPLC 2007 June 17 - 21, Ghent, Belgium; PBA 2008, June 8 - 12, Gdansk, Poland
Content Type:
Posters
Content Subtype:
HPLC
Related Products:
In this paper we describe the use of sub 2µm porous particle LC coupled with hybrid quadrupole time of flight mass spectrometry for profiling and identification of the impurities of the cholesterol- lowering medicine Simvastatin (20mg tablet). 

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