Antibody Drug Conjugate (ADC) Load Characterization and Analysis Using the BioAccord and Nano DSC Systems

Library Number:
APNT135047770
Part Number:
720006810EN
Author(s):
Colette Quinn and Henry Shion
Source:
Waters
Content Type:
Application Notes
Content Subtype:
Technical Notes
Related Products:
 

Physicochemical characterization is a strategy that ensures expanded understanding of the biologic system of interest. It takes a molecule through the analytics of biochemical characterization to identify critical quality attributes, into biophysical characterization, with confidence from discoveries supported by orthogonal platforms that confirm assertions made independently. The synergies obtainable from elements of the Waters/TA instrument portfolio, the BioAccord System and Nano DSC, enables a physicochemical strategy that facilitates a rigorous and complementary assessment of the molecule’s chemical and physical properties.


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