Intact Trastuzumab Monoclonal Antibody Quantification Using the Xevo G2-XS QTof High Resolution Mass Spectrometer

Library Number:
Part Number:
Yun Wang Alelyunas, Henry Shion, Ian Edwards, and Mark Wrona
Content Type:
Application Notes
Content Subtype:
Technical Notes
Related Products:

This technology brief demonstrates the performance of the Xevo™ G2-XS QTof platform for intact level quantification of trastuzumab monoclonal antibody and the use of UNIFI™ for rapid data processing and analysis. In the present study, a monoclonal antibody, trastuzumab, was quantified at the intact level through integration of XICs, which follows common practice in small molecule and peptide bioanalysis. 

Title Format File Size
720006379EN PDF 1085.47kB