Faster Sample Analysis of Fat Soluble Vitamins using CORTECS C8 Columns

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Kenneth Berthelette, Thomas Swann
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Application Notes
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This technology brief demonstrates how to achieve faster analysis of extremely hydrophobic compounds.

CORTECS UPLC C8 Columns contain solid-core particles with a trifunctionally bonded C8 ligand attached. Similar to columns with a C18 ligand, the CORTECS UPLC Columns offer approximately the same selectivity; however due to the shorter alkyl chain, the CORTECS UPLC C8 Column is less hydrophobic. The decreased hydrophobicity of the column leads to decreased retention times of many compounds, which can advantageous when analyzing extremely hydrophobic analytes such as fat soluble vitamins.

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