Method Transfer and Reliability of the ACQUITY Arc for Peptide Mapping

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Brooke M. Koshel and Sean M. McCarthy
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Application Notes
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Application Notes
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This application note demonstrates the method equivalency of a peptide map method when transferred between LC platforms.

The ACQUITY Arc System has the ability to emulate legacy HPLC methods, but also allows HPLC methods to be updated to UHPLC methods with the use of Arc Multi-flow path technology. By updating an HPLC method to a UHPLC method and incorporating the ACQUITY QDa Detector, routine mass detection can be incorporated into analysis to aid in confirmation of results.

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