High Sensitivity Quantification of Infliximab in Rat Plasma Using a Fast, Standardized Kit-Based Approach

Library Number:
APNT134868864
Part Number:
720005535EN
Author(s):
Mary Lame, Hua Yang, Sherri Naughton, Erin Chambers
Source:
Waters
Content Type:
Application Notes
Content Subtype:
Application Notes
Related Products:
 
Protein Quantification
 
 

This application note describes the fast, sensitive quantification of infliximab from rat plasma using the ProteinWorks eXpress Digest Kit and Protocol.

The ProteinWorks eXpress Digest Kit was successfully used to purify infliximab from a typical set of standard curve and QC samples in rat plasma. A limit of quantification of 10 ng/mL was readily achieved, while maintaining excellent linearity and single digit precision.


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