Analysis of the Non-Ionic Surfactant Triton-X Using UltraPerformance Convergence Chromatography (UPC2) with MS and UV Detection

Library Number:
APNT134863988
Part Number:
720005496en
Author(s):
Jane Cooper and Baiba Cabovska
Source:
Waters
Content Type:
Application Notes
Content Subtype:
Application Notes
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In this application note, we present a novel method to monitor the composition, detect impurities, contaminants, degradation and by-products present in surfactants, as well as identify potential carcinogenic or allergenic compounds. Excellent resolution for approximately 20 oligomers has been achieved using lower temperatures than GC or traditional SFC analysis, making UltraPerformance Convergence Chromatography (UPC2) more amenable for the analysis of thermally labile compounds. A significant reduction in the consumption of toxic solvents was also achieved compared to normal phase HPLC analysis.


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