ACQUITY UPLC M-Class System: Small Molecule Chromatographic Performance with 1.0-mm Diameter Microscale Columns

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Daniel Root, Thomas Wheat
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Application Notes
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Technical Notes
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This technology brief demonstrates chromatographic performance of the ACQUITY UPLC® M-Class System for small molecule separations on 1.0-mm diameter columns packed with sub-2-μm particles.

To satisfy the desire of many laboratories to enhance the sensitivity of their analyses, the ACQUITY UPLC M-Class System was designed as a flexible system for nano- to-microscale separations. Highly repeatable, accurate solvent delivery and sample introduction, as well as appropriately scaled detection, enable the ACQUITY UPLC M-Class System to deliver repeatable and reliable results from 1.0-mm diameter microscale separations.

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