Screening for Cannabinoids Using the Waters Forensic Toxicology Application Solution with UNIFI

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Rob Lee and Michelle Wood
Content Type:
Application Notes
Content Subtype:
Application Notes
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Xevo G2-S QTof

This application note demonstrates the sensitivity and selectivity of the expanded Forensic Toxicology Application Solution with UNIFI using negative ionization in providing a consistent comprehensive determination of cannabinoids. It can be applied as both a screen for selected cannabinoids and a method suitable for quantifying these analytes, at levels below the current EWDTS urine screening cut-off (50 ng/mL for cannabis metabolites), using a simple five-fold dilution. The excellent linear dynamic range of this system is demonstrated by simple automatically generated calibration plots.

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