Lipid Visualization and Identification Through Collisional Cross Section Aided Correlation of MS Imaging and Ex Situ MS Data for MS-MS Identification

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Mark Towers, Emmanuelle Claude
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Application Notes
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Technical Notes
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Discovery Bioanalysis


Collisional cross section (CCS) areas can be utilized as an additional chemical property to aid in the comparison of datasets. This is particularly true when analyzing samples that may contain a large number of isobaric or near isobaric species. The use of CCS areas provided an additional level of confidence regarding the molecular identification. It supplemented and confirmed the results obtained from the accurate mass analysis, and let to a more definitive identification of the lipid species of interest.


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