Metabolic Phenotyping Using Atmospheric Pressure Gas Chromatography-MS

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Vladimir Shulaev, Ghaste Manoj, Steven Lai, Carolina Salazar, Nobuhiro Suzuki, Janna Crossley, Feroza Kaneez Coudhury, Khadiza Zaman, Ron Mittler, James Langridge, Robert Plumb, Fulvio Mattivi, Giuseppe Astarita
Waters, University of North Texas, Denton, Fondazione Edmund Mach, San Michele all’Adige
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Application Notes
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Application Notes
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This application note reports an APGC-TOF MSE profiling approach and its application to metabolic fingerprinting of Arabidopsis.

APGC-TOF MSE with Progenesis QI is a valuable solution for metabolomics applications. The use of orthogonal information for the metabolite identification, including accurate mass, retention time, and theoretical or measured fragmentation, increased the confidence of metabolite identification while decreasing the number of false positive identifications.

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