Best Practices Changing from Aqueous to Organic Mobile Phase While Using Advanced Polymer Chromatography

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Jennifer Gough
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White Papers

The Advanced Polymer Chromatography (APC) System offers mobile phase flexibility by enabling both aqueous and aggressive solvent use. This system capability requires mobile phase best practices, and this document will support the scientist in successfully making the transition. The detailed instructions and supporting references will guide the user through the process of changing mobile phases, while lowering the risk of precipitating non-miscible polymer solutions and solvents. The liquid chromatographic analysis of polymers and polymer matrices can be challenging, and the APC with p-ISM or p-QSM offers greater solvent flexibility for a wide variety of polymer chemistry and solubility.

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