Increased Specificity, Improved Lipidomic Clarity, and Identification Confidence with SONAR

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Adam King, Lee A. Gethings, Robert S. Plumb, and Ian D. Wilson
Waters, Imperial College London
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Application Notes
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Technical Notes
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This study demonstrates the benefits of SONAR for omics studies, providing enhanced specificity, clearer spectra, and ultimately fewer false positives when conducting compound database searches. A comparison of SONAR with an alternative DIA methodology shows how increased specificity in the workflow can reduce false positives that result from simultaneous fragmentation from multiple species within the collision cell.

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