Characteristics of Proteomics Experiments Performed on the SYNAPT XS Q-ToF Mass Spectrometer

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Christopher Hughes and Lee Gethings
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Application Notes
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This study demonstrates the performance characteristics of the SYNAPT XS Mass Spectrometer coupled with an ACQUITY UPLC M-Class nanoscale chromatography system for the analysis of medium to complex proteomic samples. The mass resolution and sensitivity of the SYNAPT XS Mass Spectrometer increases peptide and protein identification rates for both the E. coli and human cell line samples when compared with the previous iteration of the SYNAPT G2-Si Mass Spectrometer. Protein identifications over a wide dynamic range and with excellent mass accuracy also highlight the potential of the new SYNAPT XS Mass Spectrometer performance characteristics.

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